On Church Street between Isabella to the north and Carlton to the south you will find more restaurants than just about anywhere in the city in a comparable distance comparable to Greektown. The restaurants often suffer in Toronto's tourist districts, this is no exception. If you have to eat here, the take-out often beats sit-down, and you get to walk. There are several good "sub" joints north of Wellesley on Church. The key here is that you are eating as part of a larger plan to be out with friends for drinks, socializing, dancing and debauchery.
Pi-Tom's Thai Cuisine
6a alexander street, at yonge (http://www.pi-tom.com). serves excellent thai food and is very consistent in offering high quality meals. lunch specials are available during day and the price is excellent. the atmosphere is very clean and quiet. pi pronounced pee means is a prefix of respect, takeout is also available. be sure to try the pumpkin soup! meals from under $10.